3MGH

Binary complex of a DNA polymerase lambda loop mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0006281	biological_process	DNA repair
A	0016779	molecular_function	nucleotidyltransferase activity
A	0034061	molecular_function	DNA polymerase activity
C	0003677	molecular_function	DNA binding
C	0003887	molecular_function	DNA-directed DNA polymerase activity
C	0006281	biological_process	DNA repair
C	0016779	molecular_function	nucleotidyltransferase activity
C	0034061	molecular_function	DNA polymerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 800

Chain	Residue
A	HOH29
A	SER339
A	ILE341
A	ALA344
P	DA5
P	HOH75

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA C 802

Chain	Residue
C	ALA344
F	DA5
C	HOH50
C	SER339
C	ILE341

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA C 803

Chain	Residue
C	ASP427
C	ASP429
C	ASP490
F	DC6

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA C 1

Chain	Residue
C	HOH16
C	CYS300
C	ILE302
C	ILE305
G	DC3

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Functional Information from PROSITE/UniProt

site_id	PS00522
Number of Residues	20
Details	DNA_POLYMERASE_X DNA polymerase family X signature. GSYrRGkatCgDVDVLIthP

Chain	Residue	Details
A	GLY416-PRO435

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Schiff-base intermediate with DNA => ECO:0000269|PubMed:11457865

Chain	Residue	Details
A	LYS312
C	LYS312

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFP, ECO:0007744|PDB:2PFQ

Chain	Residue	Details
A	ARG386
A	SER417
A	GLY426
A	ASN513
C	ARG386
C	SER417
C	GLY426
C	ASN513

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFO, ECO:0007744|PDB:2PFQ

Chain	Residue	Details
A	ASP427
A	ASP429
A	ASP490
C	ASP427
C	ASP429
C	ASP490

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