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3MEC

HIV-1 Reverse Transcriptase in Complex with TMC125

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
p66 Reverse transcriptasepolymer56064562.91UniProt (P04585)
Pfam (PF00078)
Pfam (PF06817)
Pfam (PF06815)
Pfam (PF00075)
HIV-1 M:B_HXB2R (HIV-1)
2B
(B)
p51 Reverse transcriptasepolymer44051399.01UniProt (P04585)
Pfam (PF00078)
Pfam (PF06817)
Pfam (PF06815)
HIV-1 M:B_HXB2R (HIV-1)
3C
(A)
4-({6-AMINO-5-BROMO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILEnon-polymer435.31Chemie (65B)
4D, E, F, G, H
(A, B)
SULFATE IONnon-polymer96.15Chemie (SO4)
5I, J
(A, B)
waterwater18.0215Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight115962.0
Non-Polymers*Number of molecules6
Total formula weight915.6
All*Total formula weight116877.6
*Water molecules are not included.

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PDB entries from 2025-12-24

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