3MDZ

Crystal Structure of Human Carbonic Anhydrase VII [isoform 1], CA7

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Carbonic anhydrase 7	polymer	281	31732.6	1	UniProt (P43166) Pfam (PF00194) In PDB	Homo sapiens (human)	CA7, Carbonic anhydrase VII, CA-VII, Carbonate dehydratase VII
2	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
3	A	6-ethoxy-1,3-benzothiazole-2-sulfonamide	non-polymer		258.3	1	Chemie (EZL)
4	A	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
5		water	water		18.0	48	Chemie (HOH)

Sequence modifications

A: 5 - 262 (UniProt: P43166)

PDB	External Database	Details
Met -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
Gly -9	-	expression tag
Val -8	-	expression tag
Asp -7	-	expression tag
Leu -6	-	expression tag
Gly -5	-	expression tag
Thr -4	-	expression tag
Glu -3	-	expression tag
Asn -2	-	expression tag
Leu -1	-	expression tag
Tyr 0	-	expression tag
Phe 1	-	expression tag
Gln 2	-	expression tag
Ser 3	-	expression tag
Met 4	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	31732.6
Non-Polymers*	Number of molecules	5
	Total formula weight	600.0
All*	Total formula weight	32332.6

*Water molecules are not included.