3MDC
DNA polymerase lambda in complex with dFdCTP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase lambda | polymer | 325 | 36405.6 | 1 | UniProt (Q9UGP5) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (human) | Pol Lambda, DNA polymerase kappa, DNA polymerase beta-2, Pol beta2 |
| 2 | B (T) | DNA (5'-D(*CP*GP*GP*CP*GP*GP*TP*AP*CP*TP*G)-3') | polymer | 11 | 3390.2 | 1 | |||
| 3 | C (P) | DNA (5'-D(*CP*AP*GP*TP*AP*C)-3') | polymer | 6 | 1793.2 | 1 | |||
| 4 | D (D) | DNA (5'-D(P*GP*CP*CP*G)-3') | polymer | 4 | 1191.8 | 1 | |||
| 5 | E (A) | 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate) | non-polymer | 503.1 | 1 | Chemie (GTF) | |||
| 6 | F, G, H, K (A) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 7 | I, J (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 8 | L, M, N, O (A, T, P, D) | water | water | 18.0 | 369 | Chemie (HOH) |
Sequence modifications
A: 252 - 575 (UniProt: Q9UGP5)
| PDB | External Database | Details |
|---|---|---|
| Ala 251 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 42780.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 643.7 | |
| All* | Total formula weight | 43424.5 |
