3M94
Complex crystal structure of Ascaris suum eIF4E-3 with m2,2,7G cap
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Translation initiation factor 4E | polymer | 189 | 22169.3 | 1 | UniProt (Q6PKX2) Pfam (PF01652) | Ascaris suum (Pig roundworm) | |
| 2 | B (C) | Eukaryotic translation initiation factor 4E-binding protein 1 | polymer | 17 | 2144.6 | 1 | UniProt (Q13541) | Homo sapiens | eIF4E-binding protein 1, 4E-BP1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, PHAS-I |
| 3 | C (A) | N,N,7-trimethylguanosine 5'-(trihydrogen diphosphate) | non-polymer | 487.3 | 1 | Chemie (M7M) | |||
| 4 | D (C) | ACETYL GROUP | non-polymer | 44.1 | 1 | Chemie (ACE) | |||
| 5 | E, F (A, C) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A: 49 - 236 (UniProt: Q6PKX2)
| PDB | External Database | Details |
|---|---|---|
| Met 48 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 24313.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 531.3 | |
| All* | Total formula weight | 24845.2 |
