3M0D
Crystal structure of the TRAF1:TRAF2:cIAP2 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | TNF receptor-associated factor 2 | polymer | 66 | 7572.6 | 2 | UniProt (Q12933) Pfam (PF16673) | Homo sapiens (human) | Tumor necrosis factor type 2 receptor-associated protein 3 |
| 2 | C (C) | TNF receptor-associated factor 1 | polymer | 65 | 7468.7 | 1 | UniProt (Q13077) Pfam (PF16673) | Homo sapiens (human) | Epstein-Barr virus-induced protein 6 |
| 3 | D (D) | Baculoviral IAP repeat-containing protein 3 | polymer | 75 | 8582.0 | 1 | UniProt (Q13489) Pfam (PF00653) | Homo sapiens (human) | Inhibitor of apoptosis protein 1, IAP-1, hIAP-1, hIAP1, C-IAP2, TNFR2-TRAF-signaling complex protein 1, IAP homolog C, Apoptosis inhibitor 2, API2, RING finger protein 49 |
| 4 | E (D) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
A, B: 266 - 329 (UniProt: Q12933)
C: 266 - 329 (UniProt: Q13077)
D: 26 - 99 (UniProt: Q13489)
| PDB | External Database | Details |
|---|---|---|
| Leu 330 | - | expression tag |
| Glu 331 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 265 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 25 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 31195.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 31261.3 |
