Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0033209 | biological_process | tumor necrosis factor-mediated signaling pathway |
| B | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0033209 | biological_process | tumor necrosis factor-mediated signaling pathway |
| C | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| C | 0042981 | biological_process | regulation of apoptotic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 401 |
| Chain | Residue |
| D | CYS66 |
| D | CYS69 |
| D | HIS86 |
| D | CYS93 |
Functional Information from PROSITE/UniProt
| site_id | PS01282 |
| Number of Residues | 68 |
| Details | BIR_REPEAT_1 BIR repeat. ElyRmstyst.Fpagvpvserslar.AGFyYtgvnDkvkCfcCglmldnWkrgdsptekHkklyPsCrfV |
| Chain | Residue | Details |
| D | GLU29-VAL96 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Region: {"description":"Important for interaction with BIRC2 and BIRC3","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"P39429","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"15468071","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 67 |
| Details | Repeat: {"description":"BIR 1"} |
