3LV8

1.8 Angstrom resolution crystal structure of a thymidylate kinase (tmk) from Vibrio cholerae O1 biovar eltor str. N16961 in complex with TMP, thymidine-5'-diphosphate and ADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Thymidylate kinase	polymer	236	26438.8	1	UniProt (Q9KQI2) Pfam (PF02223)	Vibrio cholerae O1 biovar eltor	dTMP kinase
2	B (A)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
3	C (A)	THYMIDINE-5'-PHOSPHATE	non-polymer		322.2	1	Chemie (TMP)
4	D (A)	THYMIDINE-5'-DIPHOSPHATE	non-polymer		402.2	1	Chemie (TYD)
5	E, F, G, H, I... (A)	CALCIUM ION	non-polymer		40.1	6	Chemie (CA)
6	K (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
7	L (A)	water	water		18.0	287	Chemie (HOH)

Sequence modifications

A: 1 - 212 (UniProt: Q9KQI2)

PDB	External Database	Details
Met -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Val -13	-	expression tag
Asp -12	-	expression tag
Leu -11	-	expression tag
Gly -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	26438.8
Non-Polymers*	Number of molecules	10
	Total formula weight	1427.5
All*	Total formula weight	27866.3

*Water molecules are not included.