Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004712 | molecular_function | protein serine/threonine/tyrosine kinase activity |
| A | 0004798 | molecular_function | thymidylate kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006227 | biological_process | dUDP biosynthetic process |
| A | 0006233 | biological_process | dTDP biosynthetic process |
| A | 0006235 | biological_process | dTTP biosynthetic process |
| A | 0009165 | biological_process | nucleotide biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016310 | biological_process | phosphorylation |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ADP A 213 |
| Chain | Residue |
| A | GLY13 |
| A | VAL194 |
| A | CA217 |
| A | HOH251 |
| A | HOH265 |
| A | HOH284 |
| A | HOH285 |
| A | HOH286 |
| A | HOH381 |
| A | HOH478 |
| A | HOH483 |
| A | ALA14 |
| A | GLY15 |
| A | LYS16 |
| A | SER17 |
| A | ARG147 |
| A | GLN189 |
| A | SER190 |
| A | ILE191 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE TMP A 214 |
| Chain | Residue |
| A | GLU12 |
| A | GLU40 |
| A | PRO41 |
| A | ARG51 |
| A | LYS55 |
| A | ARG76 |
| A | ARG98 |
| A | SER102 |
| A | SER103 |
| A | TYR106 |
| A | GLN107 |
| A | ILE157 |
| A | CA218 |
| A | HOH327 |
| A | HOH353 |
| A | HOH381 |
| A | HOH477 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE TYD A 215 |
| Chain | Residue |
| A | GLU12 |
| A | GLU40 |
| A | ARG51 |
| A | LYS55 |
| A | VAL72 |
| A | ARG76 |
| A | ARG98 |
| A | SER102 |
| A | SER103 |
| A | TYR106 |
| A | GLN107 |
| A | GLU158 |
| A | CA217 |
| A | CA218 |
| A | HOH230 |
| A | HOH265 |
| A | HOH327 |
| A | HOH353 |
| A | HOH381 |
| A | HOH434 |
| A | HOH476 |
| A | HOH477 |
| A | HOH490 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 216 |
| Chain | Residue |
| A | GLU92 |
| A | HOH314 |
| A | HOH441 |
| A | HOH479 |
| A | HOH480 |
| A | HOH481 |
| A | HOH482 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 217 |
| Chain | Residue |
| A | ADP213 |
| A | TYD215 |
| A | HOH265 |
| A | HOH475 |
| A | HOH476 |
| A | HOH477 |
| A | HOH478 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 218 |
| Chain | Residue |
| A | GLU12 |
| A | GLU158 |
| A | TMP214 |
| A | TYD215 |
| A | HOH327 |
| A | HOH434 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 219 |
| Chain | Residue |
| A | ALA176 |
| A | ASP179 |
| A | VAL182 |
| A | HOH231 |
| A | HOH232 |
| A | HOH392 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 220 |
| Chain | Residue |
| A | ASN177 |
| A | HOH267 |
| A | HOH268 |
| A | HOH291 |
| A | HOH292 |
| A | HOH293 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 221 |
| Chain | Residue |
| A | LYS130 |
| A | HOH225 |
| A | HOH266 |
| A | HOH328 |
| A | HOH379 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 222 |
| Chain | Residue |
| A | ARG111 |
| A | HOH362 |
| A | HOH411 |
Functional Information from PROSITE/UniProt
| site_id | PS01331 |
| Number of Residues | 13 |
| Details | THYMIDYLATE_KINASE Thymidylate kinase signature. VGDRHdmSSqAYQ |
| Chain | Residue | Details |
| A | VAL95-GLN107 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY10 | |
