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3LUK

Crystal structure of MID domain from hAGO2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Protein argonaute-2polymer13815513.53UniProt (Q9UKV8)
Pfam (PF16487)
Homo sapiens (human)Argonaute2, hAgo2, Protein slicer, PAZ Piwi domain protein, PPD, Eukaryotic translation initiation factor 2C 2, eIF-2C 2, eIF2C 2
2D, E, G, H, I...
(A, B, C)
PHOSPHATE IONnon-polymer95.08Chemie (PO4)
3F
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4M, N, O
(A, B, C)
waterwater18.0570Chemie (HOH)
Sequence modifications
A, B, C: 439 - 575 (UniProt: Q9UKV8)
PDBExternal DatabaseDetails
Ser 438-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight46540.6
Non-Polymers*Number of molecules9
Total formula weight851.9
All*Total formula weight47392.5
*Water molecules are not included.

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PDB entries from 2025-12-24

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