3LSF
Piracetam bound to the ligand binding domain of GluA2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (B, E, H) | Glutamate receptor 2 | polymer | 258 | 28808.3 | 3 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (brown rat rat rats) | GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, AMPA-selective glutamate receptor 2 |
| 2 | D, G, M (B, E, H) | GLUTAMIC ACID | non-polymer | 147.1 | 3 | Chemie (GLU) | |||
| 3 | E, F, H, I, N... (B, E, H) | 2-(2-oxopyrrolidin-1-yl)acetamide | non-polymer | 142.2 | 6 | Chemie (PZI) | |||
| 4 | J, K, L, P, Q (E, H) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 5 | R, S, T (B, E, H) | water | water | 18.0 | 867 | Chemie (HOH) |
Sequence modifications
B, E, H: 4 - 117 (UniProt: P19491)
B, E, H: 120 - 261 (UniProt: P19491)
B, E, H: 120 - 261 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | linker |
| Thr 119 | - | linker |
| Ser 242 | Asn 775 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 86424.9 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1621.4 | |
| All* | Total formula weight | 88046.3 |
