3LRN

Crystal structure of human RIG-I CTD bound to a 14 bp GC 5' ppp dsRNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Probable ATP-dependent RNA helicase DDX58	polymer	121	14203.5	2	UniProt (O95786) Pfam (PF11648) In PDB	Homo sapiens (human)	DEAD-box protein 58, Retinoic acid-inducible gene 1 protein, RIG-1, Retinoic acid-inducible gene I protein, RIG-I
2	C, D	RNA (5'-R(*(GTP)P*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3')	polymer	14	4667.7	2
3	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4		water	water		18.0	54	Chemie (HOH)

Sequence modifications

A, B: 803 - 923 (UniProt: O95786)

PDB	External Database	Details
Ser 829	Cys 829	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	37742.5
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	37873.3

*Water molecules are not included.