3LRN
Crystal structure of human RIG-I CTD bound to a 14 bp GC 5' ppp dsRNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Probable ATP-dependent RNA helicase DDX58 | polymer | 121 | 14203.5 | 2 | UniProt (O95786) Pfam (PF11648) | Homo sapiens (human) | DEAD-box protein 58, Retinoic acid-inducible gene 1 protein, RIG-1, Retinoic acid-inducible gene I protein, RIG-I |
| 2 | C, D (C, D) | RNA (5'-R(*(GTP)P*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3') | polymer | 14 | 4667.7 | 2 | |||
| 3 | E, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 54 | Chemie (HOH) |
Sequence modifications
A, B: 803 - 923 (UniProt: O95786)
| PDB | External Database | Details |
|---|---|---|
| Ser 829 | Cys 829 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 37742.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 37873.3 |
