3LQ3
Crystal structure of human choline kinase beta in complex with phosphorylated hemicholinium-3 and adenosine nucleotide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Choline/ethanolamine kinase | polymer | 401 | 46265.3 | 1 | UniProt (Q9Y259) Pfam (PF01633) | Homo sapiens (human) | choline/ethanolamine kinase beta, CKEKB, Choline kinase beta, CKB, CK, Choline kinase-like protein, Ethanolamine kinase, EK, Ethanolamine kinase beta, EKB |
| 2 | B (A) | (2S)-2-[4'-({dimethyl[2-(phosphonooxy)ethyl]ammonio}acetyl)biphenyl-4-yl]-2-hydroxy-4,4-dimethylmorpholin-4-ium | non-polymer | 494.5 | 1 | Chemie (HC7) PubChem (25113187) PubChem (45259046) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 4 | D, E (A) | UNKNOWN ATOM OR ION | non-polymer | 2 | Chemie (UNX) | ||||
| 5 | F (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | G (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 7 | H (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (40467049) PubChem (40469468) PubChem (34768) PubChem (44348067) PubChem (83862) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (46875232) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (5316444) PubChem (92144436) PubChem (5742864) PubChem (122197642) PubChem (12358354) PubChem (12163610) PubChem (12358355) PubChem (162290139) PubChem (162946266) PubChem (171699505) | |||
| 8 | I (A) | water | water | 18.0 | 273 | Chemie (HOH) |
Sequence modifications
A: 14 - 395 (UniProt: Q9Y259)
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| His 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
| Ser 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Gly 7 | - | expression tag |
| Leu 8 | - | expression tag |
| Val 9 | - | expression tag |
| Pro 10 | - | expression tag |
| Arg 11 | - | expression tag |
| Gly 12 | - | expression tag |
| Ser 13 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 46265.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1389.3 | |
| All* | Total formula weight | 47654.6 |
