3LPU
HIV integrase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrase | polymer | 166 | 18434.7 | 1 | UniProt (Q76353) Pfam (PF00665) UniProt (by SIFTS) (P12497) | Human immunodeficiency virus 1 | |
| 2 | B (A) | (2S)-2-(6-chloro-2-methyl-4-phenylquinolin-3-yl)pentanoic acid | non-polymer | 353.8 | 1 | Chemie (976) | |||
| 3 | C (A) | 2-[3-[3-(2-hydroxyethoxy)propoxy]propoxy]ethanol | non-polymer | 222.3 | 1 | Chemie (P03) | |||
| 4 | D, E (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 5 | F, G, H (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | I (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | J (A) | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
A: 50 - 212 (UniProt: Q76353)
| PDB | External Database | Details |
|---|---|---|
| Gly 47 | - | expression tag |
| Ser 48 | - | expression tag |
| His 49 | - | expression tag |
| Lys 185 | Phe 185 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18434.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1116.6 | |
| All* | Total formula weight | 19551.4 |
