3LPH
Crystal structure of the HIV-1 Rev dimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Protein Rev | polymer | 72 | 8438.5 | 4 | UniProt (P69718) Pfam (PF00424) | Human immunodeficiency virus type 1 (HIV-1) | Regulator of expression of viral proteins, Anti-repression transactivator, ART/TRS |
| 2 | E, F (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | G, H, I, K, L... (A, B, C, D) | BROMIDE ION | non-polymer | 79.9 | 13 | Chemie (BR) | |||
| 4 | J, O (A, B) | MALONATE ION | non-polymer | 102.0 | 2 | Chemie (MLI) | |||
| 5 | V, W, X, Y (A, B, C, D) | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 70 (UniProt: P69718)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ser 12 | Leu 12 | engineered mutation |
| Arg 60 | Leu 60 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 33753.8 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1435.0 | |
| All* | Total formula weight | 35188.8 |
