3LPH
Crystal structure of the HIV-1 Rev dimer
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0042025 | cellular_component | host cell nucleus |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0042025 | cellular_component | host cell nucleus |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0042025 | cellular_component | host cell nucleus |
| D | 0003700 | molecular_function | DNA-binding transcription factor activity |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0042025 | cellular_component | host cell nucleus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 71 |
| Chain | Residue |
| A | ARG39 |
| A | ARG42 |
| A | ARG46 |
| A | HOH78 |
| A | HOH92 |
| C | ARG42 |
| C | ARG46 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 72 |
| Chain | Residue |
| A | ARG48 |
| B | ARG58 |
| A | ARG41 |
| A | ARG44 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR A 73 |
| Chain | Residue |
| A | ARG42 |
| A | MLI76 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR D 71 |
| Chain | Residue |
| A | GLY65 |
| D | ARG60 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BR A 74 |
| Chain | Residue |
| A | HOH94 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BR A 75 |
| Chain | Residue |
| A | ALA37 |
| A | ASN40 |
| A | ARG43 |
| A | ARG44 |
| A | HOH82 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BR B 71 |
| Chain | Residue |
| B | THR34 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR B 72 |
| Chain | Residue |
| B | ARG17 |
| B | HOH87 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BR B 73 |
| Chain | Residue |
| B | ARG60 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR B 74 |
| Chain | Residue |
| B | ARG60 |
| C | LYS20 |
| site_id | BC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BR D 72 |
| Chain | Residue |
| B | HOH88 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BR C 73 |
| Chain | Residue |
| D | HOH81 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR C 74 |
| Chain | Residue |
| C | ARG46 |
| C | ARG46 |
| site_id | BC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MLI A 76 |
| Chain | Residue |
| A | PRO31 |
| A | ARG35 |
| A | ARG38 |
| A | ARG42 |
| A | BR73 |
| C | TRP45 |
| C | GLN49 |
| C | HIS53 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MLI B 75 |
| Chain | Residue |
| B | GLN36 |
| B | ALA37 |
| B | ASN40 |
| B | ARG44 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | MOD_RES: Phosphoserine; by host CK2 => ECO:0000255|HAMAP-Rule:MF_04077 |
| Chain | Residue | Details |
| A | SER5 | |
| A | SER8 | |
| B | SER5 | |
| B | SER8 | |
| C | SER5 | |
| C | SER8 | |
| D | SER5 | |
| D | SER8 |
