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3LNJ

Crystal structure of human MDM2 in complex with D-peptide inhibitor (DPMI-alpha)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E
(A, C, E)
E3 ubiquitin-protein ligase Mdm2polymer8510044.93UniProt (Q00987)
Pfam (PF02201)
p53-binding protein Mdm2, Oncoprotein Mdm2, Double minute 2 protein, Hdm2
2B, D, F
(B, D, F)
D-peptide inhibitorpolymer121521.73BIRD (PRD_000808)
3G
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4H
(C)
CHLORIDE IONnon-polymer35.51Chemie (CL)
5I
(E)
GLYCEROLnon-polymer92.11Chemie (GOL)
6J, K, L, M, N...
(A, B, C, D, E...)
waterwater18.061Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight34699.9
Non-Polymers*Number of molecules3
Total formula weight223.6
All*Total formula weight34923.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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