3LMI
Crystal Structure of the Inactive Alpha-kinase Domain of Myosin Heavy Chain Kinase A (D766A) complex with ATP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Myosin heavy chain kinase A | polymer | 307 | 34482.6 | 4 | UniProt (P42527) Pfam (PF02816) In PDB | Dictyostelium discoideum (Slime mold) | MHCK-A |
2 | A, B, C, D | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
3 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
4 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
5 | A, B, C, D | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 4 | Chemie (ATP) | |||
6 | water | water | 18.0 | 571 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 552 - 841 (UniProt: P42527)
PDB | External Database | Details |
---|---|---|
Met 535 | - | expression tag |
Gly 536 | - | expression tag |
Gly 537 | - | expression tag |
His 538 | - | expression tag |
His 539 | - | expression tag |
His 540 | - | expression tag |
His 541 | - | expression tag |
His 542 | - | expression tag |
His 543 | - | expression tag |
Gly 544 | - | expression tag |
Glu 545 | - | expression tag |
Asn 546 | - | expression tag |
Leu 547 | - | expression tag |
Tyr 548 | - | expression tag |
Phe 549 | - | expression tag |
Gln 550 | - | expression tag |
Gly 551 | - | expression tag |
Ala 766 | Asp 766 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 137930.3 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 2957.4 | |
All* | Total formula weight | 140887.7 |