3LLR
Crystal structure of the PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 alpha
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | DNA (cytosine-5)-methyltransferase 3A | polymer | 154 | 17260.5 | 5 | UniProt (Q9Y6K1) Pfam (PF00855) | Homo sapiens (human) | Dnmt3a, DNA methyltransferase HsaIIIA, DNA MTase HsaIIIA, M.HsaIIIA |
| 2 | F, G, I, J, K (A, B, C, D, E) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 5 | Chemie (BTB) | |||
| 3 | H (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | L, M, N, O, P (A, B, C, D, E) | water | water | 18.0 | 362 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 153 (UniProt: Q9Y6K1)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 86302.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1142.3 | |
| All* | Total formula weight | 87444.8 |
