3LH0
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K372me2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tumor suppressor p53-binding protein 1 | polymer | 125 | 14029.8 | 1 | UniProt (Q12888) Pfam (PF09038) | Homo sapiens (human) | p53-binding protein 1, p53BP1, 53BP1 |
| 2 | B (B) | DIMETHYLATED p53 LYSINE 372 PEPTIDE | polymer | 11 | 1231.4 | 1 | |||
| 3 | C, D (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 4 | E (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence modifications
A: 1484 - 1603 (UniProt: Q12888)
| PDB | External Database | Details |
|---|---|---|
| Gly 1479 | - | expression tag |
| Pro 1480 | - | expression tag |
| Leu 1481 | - | expression tag |
| Gly 1482 | - | expression tag |
| Ser 1483 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 15261.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 396.4 | |
| All* | Total formula weight | 15657.7 |
