3LEV
HIV-1 antibody 2F5 in complex with epitope scaffold ES2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | RNA polymerase sigma factor | polymer | 179 | 20209.3 | 1 | UniProt (Q9EZJ8) Pfam (PF00140) Pfam (PF04542) In PDB | Thermus aquaticus | |
2 | L | 2F5 ANTIBODY LIGHT CHAIN | polymer | 214 | 23305.8 | 1 | Homo sapiens (human) | ||
3 | H | 2F5 ANTIBODY HEAVY CHAIN | polymer | 237 | 25229.7 | 1 | Homo sapiens (human) | ||
4 | L | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
5 | H | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
6 | H | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
7 | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A: 93 - 271 (UniProt: Q9EZJ8)
PDB | External Database | Details |
---|---|---|
Glu 105 | Gln 105 | engineered mutation |
Leu 107 | Pro 107 | engineered mutation |
Glu 108 | Leu 108 | engineered mutation |
Asp 110 | Thr 110 | engineered mutation |
Lys 111 | Leu 111 | engineered mutation |
Trp 112 | Glu 112 | engineered mutation |
Ala 113 | Glu 113 | engineered mutation |
Leu 115 | Ile 115 | engineered mutation |
Gly 116 | Asp 116 | engineered mutation |
Ala 117 | Leu 117 | engineered mutation |
Ala 119 | Arg 119 | engineered mutation |
Ala 155 | Arg 155 | engineered mutation |
Gly 247 | Arg 247 | engineered mutation |
Ala 249 | Lys 249 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 68744.9 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 837.6 | |
All* | Total formula weight | 69582.4 |