3LEV

HIV-1 antibody 2F5 in complex with epitope scaffold ES2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006352	biological_process	DNA-templated transcription initiation
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE 1PE L 215

Chain	Residue
L	SER9
L	PRO40
L	GLY41
L	TYR87
L	GLY101
L	ARG103

---

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE ATP H 219

Chain	Residue
A	LYS179
A	LYS186
A	LEU189
A	ARG193
A	SER212
H	PRO61
H	ASN64
H	THR65
H	HOH257
A	ARG97
A	LYS149
A	ASP175

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL H 220

Chain	Residue
H	ARG100
H	HOH283
H	HOH284
H	HOH285
H	HOH286
H	HOH287

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
L	TYR192-HIS198
H	TYR194-HIS200

---

site_id	PS00867
Number of Residues	8
Details	CPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. LIEANLRL

Chain	Residue	Details
A	LEU202-LEU209

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	35
Details	Region: {"description":"Sigma-70 factor domain-1"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	3
Details	Motif: {"description":"Interaction with polymerase core subunit RpoC"}

Chain

Residue

Details

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