3LEE

Crystal structure of the human squalene synthase complexed with BPH-652

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Squalene synthetase	polymer	340	39166.7	6	UniProt (P37268) Pfam (PF00494)	Homo sapiens (human)	SQS, SS, Farnesyl-diphosphate farnesyltransferase, FPP:FPP farnesyltransferase
2	G, I, K, M, O... (A, B, C, D, E...)	(1R)-4-(3-phenoxyphenyl)-1-phosphonobutane-1-sulfonic acid	non-polymer		386.4	6	Chemie (B65)
3	H, J, L, N, P... (A, B, C, D, E...)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
4	S, T, U, V, W... (A, B, C, D, E...)	water	water		18.0	188	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	235000.2
Non-Polymers*	Number of molecules	12
	Total formula weight	2464.0
All*	Total formula weight	237464.2

*Water molecules are not included.