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3LDL

Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with ATP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
78 kDa glucose-regulated proteinpolymer38442299.92UniProt (P11021)
Pfam (PF00012)
Homo sapiens (human)GRP 78, Heat shock 70 kDa protein 5, Immunoglobulin heavy chain-binding protein, BiP, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78
2C, D
(A, B)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.22Chemie (ATP)
3E
(B)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4F, G
(A, B)
waterwater18.0451Chemie (HOH)
Sequence modifications
A, B: 26 - 407 (UniProt: P11021)
PDBExternal DatabaseDetails
Gly 24-expression tag
Ser 25-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight84599.7
Non-Polymers*Number of molecules3
Total formula weight1038.7
All*Total formula weight85638.4
*Water molecules are not included.

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PDB entries from 2025-07-23

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