3LCT
Crystal Structure of the Anaplastic Lymphoma Kinase Catalytic Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ALK tyrosine kinase receptor | polymer | 344 | 38641.3 | 1 | UniProt (Q9UM73) Pfam (PF07714) | Homo sapiens (human) | Anaplastic lymphoma kinase |
| 2 | B, D (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 3 | C (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | E (A) | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence modifications
A: 1072 - 1410 (UniProt: Q9UM73)
| PDB | External Database | Details |
|---|---|---|
| Gly 1067 | - | expression tag |
| Ala 1068 | - | expression tag |
| Met 1069 | - | expression tag |
| Gly 1070 | - | expression tag |
| Ser 1071 | - | expression tag |
| Gly 1281 | Ser 1281 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38641.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 611.4 | |
| All* | Total formula weight | 39252.7 |
