Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0004714 | molecular_function | transmembrane receptor protein tyrosine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
A | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 1 |
Chain | Residue |
A | HOH3 |
A | ILE1171 |
A | SER1172 |
A | PHE1174 |
A | ASN1175 |
A | ARG1181 |
A | CYS1182 |
site_id | AC2 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE ADP A 1412 |
Chain | Residue |
A | HIS1124 |
A | GLY1125 |
A | VAL1130 |
A | ALA1148 |
A | GLU1197 |
A | MET1199 |
A | ASP1203 |
A | LEU1256 |
A | ASP1270 |
A | HOH82 |
A | LEU1122 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL A 1411 |
Chain | Residue |
A | HIS1244 |
A | PHE1245 |
A | ILE1246 |
A | ARG1248 |
A | ALA1274 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 29 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGHGAFGEVYeGqvsgmpndpsplq.....VAVK |
Chain | Residue | Details |
A | LEU1122-LYS1150 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FIHrDIAARNCLL |
Chain | Residue | Details |
A | PHE1245-LEU1257 | |
site_id | PS00239 |
Number of Residues | 9 |
Details | RECEPTOR_TYR_KIN_II Receptor tyrosine kinase class II signature. DIYragYYR |
Chain | Residue | Details |
A | ASP1276-ARG1284 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP1249 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: |
Chain | Residue | Details |
A | HIS1124 | |
A | GLU1197 | |
Chain | Residue | Details |
A | LYS1150 | |
Chain | Residue | Details |
A | ASP1270 | |
Chain | Residue | Details |
A | TYR1078 | |
A | TYR1131 | |
Chain | Residue | Details |
A | TYR1092 | |
Chain | Residue | Details |
A | TYR1096 | |
Chain | Residue | Details |
A | TYR1278 | |