3LB6
The structure of IL-13 in complex with IL-13Ralpha2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-13 | polymer | 132 | 14333.8 | 1 | UniProt (P35225) Pfam (PF03487) | Homo sapiens (human) | IL-13 |
| 2 | B (C) | Interleukin-13 receptor subunit alpha-2 | polymer | 380 | 44253.3 | 1 | UniProt (A8K7E2) Pfam (PF09240) UniProt (by SIFTS) (Q14627) | Homo sapiens (human) | |
| 3 | C (B) | Interleukin-13 | polymer | 132 | 14360.9 | 1 | UniProt (P35225) Pfam (PF03487) | Homo sapiens (human) | |
| 4 | D (D) | Interleukin-13 receptor subunit alpha-2 | polymer | 380 | 44253.3 | 1 | UniProt (A8K7E2) Pfam (PF09240) UniProt (by SIFTS) (Q14627) | Homo sapiens (human) | |
| 5 | E, G (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 6 | F, H (C, D) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 7 | I, J, K, L (A, C, B, D) | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence modifications
C: 1 - 380 (UniProt: A8K7E2)
D: 1 - 380 (UniProt: A8K7E2)
| PDB | External Database | Details |
|---|---|---|
| Gln 151 | Arg 151 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gln 151 | Arg 151 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 117201.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 522.6 | |
| All* | Total formula weight | 117723.8 |
