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3LB6

The structure of IL-13 in complex with IL-13Ralpha2

Functional Information from GO Data
ChainGOidnamespacecontents
A0005126molecular_functioncytokine receptor binding
A0005576cellular_componentextracellular region
A0006955biological_processimmune response
B0005126molecular_functioncytokine receptor binding
B0005576cellular_componentextracellular region
B0006955biological_processimmune response
C0004896molecular_functioncytokine receptor activity
C0016020cellular_componentmembrane
D0004896molecular_functioncytokine receptor activity
D0016020cellular_componentmembrane
Functional Information from PROSITE/UniProt
site_idPS00838
Number of Residues28
DetailsINTERLEUKIN_4_13 Interleukins -4 and -13 signature. LrELIeelvnITqnqkaplCngsmVwSI
ChainResidueDetails
ALEU10-ILE37
BLEU10-ILE37

site_idPS01356
Number of Residues32
DetailsHEMATOPO_REC_S_F2 Short hematopoietin receptor family 2 signature. LlCsWkpGigvllDtnYnLfywyegldhalq..C
ChainResidueDetails
CLEU153-CYS184
DLEU153-CYS184

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues316
DetailsTOPO_DOM: Extracellular => ECO:0000255
ChainResidueDetails
DASP27-ARG343
BASN30
BASN38
BASN53

site_idSWS_FT_FI2
Number of Residues19
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
DPHE344-LEU363

site_idSWS_FT_FI3
Number of Residues16
DetailsTOPO_DOM: Cytoplasmic => ECO:0000255
ChainResidueDetails
DARG364-THR380

site_idSWS_FT_FI4
Number of Residues3
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
DASN115
DASN290
DASN299

site_idSWS_FT_FI5
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:20223216
ChainResidueDetails
DASN215

227933

PDB entries from 2024-11-27

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