3L6R

The structure of mammalian serine racemase: Evidence for conformational changes upon inhibitor binding

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Serine racemase	polymer	346	37918.4	1	UniProt (Q9GZT4) Pfam (PF00291) In PDB	Homo sapiens (human)
2	A	MALONATE ION	non-polymer		102.0	1	Chemie (MLI)
3	A	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN)
4		water	water		18.0	353	Chemie (HOH)

Sequence modifications

A: 1 - 340 (UniProt: Q9GZT4)

PDB	External Database	Details
Asp 2	Cys 2	engineered mutation
Asp 6	Cys 6	engineered mutation
His 341	-	expression tag
His 342	-	expression tag
His 343	-	expression tag
His 344	-	expression tag
His 345	-	expression tag
His 346	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	37918.4
Non-Polymers*	Number of molecules	2
	Total formula weight	157.0
All*	Total formula weight	38075.4

*Water molecules are not included.