3L5E

Structure of BACE Bound to SCH736062

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Beta-secretase 1	polymer	414	46249.9	2	UniProt (P56817) Pfam (PF00026)	Homo sapiens (human)	Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Membrane-associated aspartic protease 2, Memapsin-2, Aspartyl protease 2, Asp 2, ASP2
2	C, E, F (A, B)	D(-)-TARTARIC ACID	non-polymer		150.1	3	Chemie (TAR)
3	D, G (A, B)	(4S)-1-(4-{[(2Z,4R)-4-(2-cyclohexylethyl)-4-(cyclohexylmethyl)-2-imino-5-oxoimidazolidin-1-yl]methyl}benzyl)-4-propylimidazolidin-2-one	non-polymer		535.8	2	Chemie (BDW)
4	H, I (A, B)	water	water		18.0	882	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	92499.9
Non-Polymers*	Number of molecules	5
	Total formula weight	1521.8
All*	Total formula weight	94021.6

*Water molecules are not included.