3L4W
Crystal complex of N-terminal Human Maltase-Glucoamylase with miglitol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Maltase-glucoamylase, intestinal | polymer | 875 | 99276.7 | 1 | UniProt (O43451) Pfam (PF00088) Pfam (PF13802) Pfam (PF01055) Pfam (PF21365) | Homo sapiens (human) | Maltase, Alpha-glucosidase, Glucoamylase, Glucan 1,4-alpha-glucosidase |
| 2 | B, C (B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | D (A) | (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol | non-polymer | 207.2 | 1 | Chemie (MIG) PubChem (51577) PubChem (441314) PubChem (6710690) PubChem (9794283) PubChem (12766463) PubChem (23622608) PubChem (40467206) PubChem (40467208) PubChem (40477191) PubChem (42052023) PubChem (45039933) PubChem (49759862) PubChem (51397099) PubChem (51400355) PubChem (124300736) PubChem (57369304) PubChem (57560749) PubChem (71225356) PubChem (69541599) PubChem (69821021) PubChem (71749029) PubChem (89813532) PubChem (93532308) PubChem (124397038) PubChem (124427653) PubChem (124582590) PubChem (134693994) PubChem (134853664) PubChem (145752189) PubChem (158646524) PubChem (168440872) PubChem (171042507) PubChem (173771382) | |||
| 4 | E, F (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 5 | G, H, I, J (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) PubChem (753) | |||
| 6 | K (A) | water | water | 18.0 | 434 | Chemie (HOH) |
Sequence modifications
A: 1 - 868 (UniProt: O43451)
| PDB | External Database | Details |
|---|---|---|
| Asp 772 | Asn 858 | variant |
| Ala 869 | - | expression tag |
| His 870 | - | expression tag |
| His 871 | - | expression tag |
| His 872 | - | expression tag |
| His 873 | - | expression tag |
| His 874 | - | expression tag |
| His 875 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 99276.7 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1018.0 | |
| All* | Total formula weight | 101143.6 |
