3L4K
Topoisomerase II-DNA cleavage complex, metal-bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA topoisomerase 2 | polymer | 757 | 88025.2 | 1 | UniProt (P06786) Pfam (PF01751) Pfam (PF16898) Pfam (PF00521) | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | DNA topoisomerase II |
| 2 | B (B) | DNA (5'-D(P*CP*CP*TP*AP*CP*TP*GP*CP*TP*AP*C)-3') | polymer | 11 | 3269.1 | 1 | |||
| 3 | C (C) | DNA (5'-D(*CP*GP*CP*GP*GP*TP*AP*GP*CP*AP*GP*TP*AP*GP*G)-3') | polymer | 15 | 4675.0 | 1 | |||
| 4 | D (D) | DNA (5'-D(P*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*)-3') | polymer | 10 | 3109.1 | 1 | |||
| 5 | E (E) | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*CP*GP*TP*CP*AP*TP*CP*C)-3') | polymer | 15 | 4529.9 | 1 | |||
| 6 | F, G, H, I, J... (A, E) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 7 | M (D) | 3'-THIO-THYMIDINE-5'-PHOSPHATE | non-polymer | 338.3 | 1 | Chemie (TSP) | |||
| 8 | O, P, Q (A, B, E) | water | water | 18.0 | 20 | Chemie (HOH) |
Sequence modifications
A: 421 - 1177 (UniProt: P06786)
| PDB | External Database | Details |
|---|---|---|
| Ptr 782 | Tyr 782 | microheterogeneity |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 103608.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 861.5 | |
| All* | Total formula weight | 104469.9 |
