3L43

Crystal structure of the dynamin 3 GTPase domain bound with GDP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Dynamin-3	polymer	319	35843.3	4	UniProt (Q9UQ16) Pfam (PF00350) Pfam (PF01031)	Homo sapiens (human)	Dynamin, T-dynamin
2	E, I, K, M (A, B, C, D)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	4	Chemie (GDP)
3	F, G, H, J, L... (A, B, C, D)	UNKNOWN ATOM OR ION	non-polymer			6	Chemie (UNX)
4	O, P, Q, R (A, B, C, D)	water	water		18.0	78	Chemie (HOH)

Sequence modifications

A, B, C, D: 6 - 306 (UniProt: Q9UQ16)

PDB	External Database	Details
Met -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
Ser -5	-	expression tag
Ser -4	-	expression tag
Gly -3	-	expression tag
Arg -2	-	expression tag
Glu -1	-	expression tag
Asn 0	-	expression tag
Leu 1	-	expression tag
Tyr 2	-	expression tag
Phe 3	-	expression tag
Gln 4	-	expression tag
Gly 5	-	expression tag
Ile 74	Val 74	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	143373.1
Non-Polymers*	Number of molecules	10
	Total formula weight	1772.8
All*	Total formula weight	145145.9

*Water molecules are not included.