3L38
Bace1 in complex with the aminopyridine Compound 44
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Beta-secretase 1 | polymer | 415 | 46441.0 | 1 | UniProt (P56817) Pfam (PF00026) In PDB | Homo sapiens (human) | Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Membrane-associated aspartic protease 2, Memapsin-2, Aspartyl protease 2, Asp 2, ASP2 |
2 | A | 6-({2-(2-chlorophenyl)-5-[4-(pyrimidin-5-yloxy)phenyl]-1H-pyrrol-1-yl}methyl)pyridin-2-amine | non-polymer | 453.9 | 1 | Chemie (879) | |||
3 | water | water | 18.0 | 122 | Chemie (HOH) |
Sequence modifications
A: 47 - 455 (UniProt: P56817)
PDB | External Database | Details |
---|---|---|
His 456 | - | expression tag |
His 457 | - | expression tag |
His 458 | - | expression tag |
His 459 | - | expression tag |
His 460 | - | expression tag |
His 461 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 46441.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 453.9 | |
All* | Total formula weight | 46894.9 |