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3L2R

Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Integrasepolymer39544456.72UniProt (P14350)
Pfam (PF17921)
Pfam (PF00665)
Pfam (PF18103)
Human spumaretrovirus (SFVcpz(hu))IN, p42In
2C
(C)
5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*TP*GP*TP*A)-3'polymer195864.81
3D
(D)
5'-D(*TP*AP*CP*AP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'polymer175163.41
4E
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
5F, L
(A, B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6G
(A)
AMMONIUM IONnon-polymer18.01Chemie (NH4)
7H, I, J, K, M
(A, B)
GLYCEROLnon-polymer92.15Chemie (GOL)
8N, O, P, Q
(A, B, C, D)
waterwater18.012Chemie (HOH)
Sequence modifications
A, B: 1 - 392 (UniProt: P14350)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
Gly 0-expression tag
Ser 217Gly 968variant
Gly 218Ser 969variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight99941.6
Non-Polymers*Number of molecules9
Total formula weight592.5
All*Total formula weight100534.1
*Water molecules are not included.

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PDB entries from 2024-10-30

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