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3L2P

Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching Between Two DNA Bound States

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA ligase 3polymer57965681.81UniProt (P49916)
Pfam (PF04675)
Pfam (PF01068)
Pfam (PF04679)
Homo sapiens (human)DNA ligase III, Polydeoxyribonucleotide synthase [ATP] 3
2B
(B)
5'-D(P*CP*GP*GP*GP*AP*TP*GP*CP*GP*TP*C)-3'polymer113390.21
3C
(C)
5'-D(*GP*TP*CP*GP*GP*AP*CP*TP*G)-3'polymer92771.81
4D
(D)
5'-D(*GP*CP*CP*AP*GP*TP*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*CP*CP*G)-3'polymer226683.31
5E
(A)
ADENOSINE MONOPHOSPHATEnon-polymer347.21Chemie (AMP)
Sequence modifications
A: 170 - 746 (UniProt: P49916)
PDBExternal DatabaseDetails
His 168-expression tag
Met 169-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight78527.1
Non-Polymers*Number of molecules1
Total formula weight347.2
All*Total formula weight78874.3
*Water molecules are not included.

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PDB entries from 2025-06-18

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