3L27
Crystal structure of Zaire Ebola VP35 interferon inhibitory domain R312A mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Polymerase cofactor VP35 | polymer | 129 | 14124.4 | 4 | UniProt (Q05127) Pfam (PF02097) | Zaire ebolavirus (ZEBOV) | |
| 2 | E, F, N, O, P... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 3 | AA, BA, CA, DA, G... (D, A, B, C) | PHOSPHATE ION | non-polymer | 95.0 | 9 | Chemie (PO4) | |||
| 4 | EA, FA, J, K, L... (D, A, B, C) | GLYCEROL | non-polymer | 92.1 | 10 | Chemie (GOL) | |||
| 5 | M (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | V, Z (C, D) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 7 | GA, HA, IA, JA (A, B, C, D) | water | water | 18.0 | 329 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 215 - 340 (UniProt: Q05127)
| PDB | External Database | Details |
|---|---|---|
| Gly 212 | - | expression tag |
| His 213 | - | expression tag |
| Met 214 | - | expression tag |
| Ala 312 | Arg 312 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 56497.6 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 2089.6 | |
| All* | Total formula weight | 58587.2 |
