3L25
Crystal structure of Zaire Ebola VP35 interferon inhibitory domain bound to 8 bp dsRNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, D, E (A, B, D, E) | Polymerase cofactor VP35 | polymer | 129 | 14210.5 | 4 | UniProt (Q05127) Pfam (PF02097) | Zaire ebolavirus (ZEBOV) | |
| 2 | C, F (C, F) | RNA (5'-R(*CP*GP*CP*AP*UP*GP*CP*G)-3') | polymer | 8 | 2541.6 | 2 | |||
| 3 | G (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | EA, H, LA, P (D, A, E, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 5 | AA, BA, FA, I, Q... (C, D, A, B, F) | SODIUM ION | non-polymer | 23.0 | 8 | Chemie (NA) | |||
| 6 | J (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | CA, DA, GA, HA, IA... (C, D, A, E, F...) | FORMIC ACID | non-polymer | 46.0 | 24 | Chemie (FMT) | |||
| 8 | SA, TA, UA, VA, WA... (A, B, C, D, E...) | water | water | 18.0 | 335 | Chemie (HOH) |
Sequence modifications
A, B, D, E: 215 - 340 (UniProt: Q05127)
| PDB | External Database | Details |
|---|---|---|
| Gly 212 | - | expression tag |
| His 213 | - | expression tag |
| Met 214 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 61925.2 | |
| Non-Polymers* | Number of molecules | 38 |
| Total formula weight | 1546.7 | |
| All* | Total formula weight | 63472.0 |
