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3KZ8

Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs (p53-DNA complex 3)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Cellular tumor antigen p53polymer20022505.62UniProt (P04637)
Pfam (PF00870)
Homo sapiens (human)Tumor suppressor p53, Phosphoprotein p53, Antigen NY-CO-13
2C
(C)
DNA (5'-D(*TP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*C)-3')polymer216441.11
3D, F
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
4E, G
(A, B)
IODIDE IONnon-polymer126.92Chemie (IOD)
PubChem (30165)
5H, I, J
(A, B, C)
waterwater18.0311Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight51452.3
Non-Polymers*Number of molecules4
Total formula weight384.6
All*Total formula weight51836.9
*Water molecules are not included.

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PDB entries from 2026-03-25

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