3KWZ
Cathepsin K in complex with a non-selective 2-cyano-pyrimidine inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cathepsin K | polymer | 215 | 23523.5 | 1 | UniProt (P43235) Pfam (PF00112) | Homo sapiens (human) | Cathepsin O, Cathepsin X, Cathepsin O2 |
| 2 | B, C, D, E, F... (A) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 3 | H (A) | 4-(3-piperidin-1-ylpropyl)-6-[3-(trifluoromethyl)phenyl]pyrimidine-2-carbonitrile | non-polymer | 374.4 | 1 | Chemie (KWZ) | |||
| 4 | I (A) | water | water | 18.0 | 153 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23523.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 950.8 | |
| All* | Total formula weight | 24474.3 |
