3KWZ

Cathepsin K in complex with a non-selective 2-cyano-pyrimidine inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Cathepsin K	polymer	215	23523.5	1	UniProt (P43235) Pfam (PF00112) In PDB	Homo sapiens (human)	Cathepsin O, Cathepsin X, Cathepsin O2
2	A	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
3	A	4-(3-piperidin-1-ylpropyl)-6-[3-(trifluoromethyl)phenyl]pyrimidine-2-carbonitrile	non-polymer		374.4	1	Chemie (KWZ)
4		water	water		18.0	153	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	23523.5
Non-Polymers*	Number of molecules	7
	Total formula weight	950.8
All*	Total formula weight	24474.3

*Water molecules are not included.