3KUT

Crystal structure of the MLLE domain of poly(A)-binding protein in complex with the binding region of Paip2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Polyadenylate-binding protein 1	polymer	88	9421.9	2	UniProt (P11940) Pfam (PF00658)	Homo sapiens (human)	Poly(A)-binding protein 1, PABP 1
2	C, D (C, D)	PAIP2 protein	polymer	17	1778.0	2	UniProt (Q6FID7) Pfam (PF07145) UniProt (by SIFTS) (Q9BPZ3)	Homo sapiens
3	E, F (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	G, H, I, J (A, B, C, D)	water	water		18.0	176	Chemie (HOH)

Sequence modifications

A, B: 544 - 626 (UniProt: P11940)

PDB	External Database	Details
Gly 539	-	expression tag
Pro 540	-	expression tag
Leu 541	-	expression tag
Gly 542	-	expression tag
Ser 543	-	expression tag

C, D: 109 - 125 (UniProt: Q6FID7)

PDB	External Database	Details
Ala 116	Lys 116	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	22399.7
Non-Polymers*	Number of molecules	2
	Total formula weight	70.9
All*	Total formula weight	22470.6

*Water molecules are not included.