3KRD
Crystal Structure of Mycobacterium Tuberculosis Proteasome in complex with Fellutamide B
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, D, F, I... | Proteasome subunit alpha | polymer | 248 | 26911.0 | 14 | UniProt (A5U4D5) Pfam (PF00227) UniProt (by SIFTS) (P9WHU1) In PDB | Mycobacterium tuberculosis | 20S proteasome alpha subunit,Proteasome core protein PrcA |
2 | C, E, G, H, J... | Proteasome subunit beta | polymer | 240 | 25274.3 | 14 | UniProt (A5U4D6) Pfam (PF00227) UniProt (by SIFTS) (P9WHT9) In PDB | Mycobacterium tuberculosis | 20S proteasome beta subunit,Proteasome core protein PrcB |
3 | a, b, c, d, e... | Fellutamide B | polymer | 3 | 373.4 | 14 | synthetic construct | ||
4 | k, l, m, n, a... | (3R)-3-HYDROXYDODECANOIC ACID | non-polymer | 216.3 | 14 | Chemie (HXD) | |||
5 | water | water | 18.0 | 2225 | Chemie (HOH) |
Sequence modifications
C, E, G, H, J, L, N, P, R, T, V, X, Z, 2: 301 - 534 (UniProt: A5U4D6)
PDB | External Database | Details |
---|---|---|
His 535 | - | expression tag |
His 536 | - | expression tag |
His 537 | - | expression tag |
His 538 | - | expression tag |
His 539 | - | expression tag |
His 540 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 42 |
Total formula weight | 735821.9 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 3028.4 | |
All* | Total formula weight | 738850.4 |