3KQX

Structure of a protease 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	M17 leucyl aminopeptidase	polymer	528	58709.0	12	UniProt (Q8IL11) Pfam (PF00883)	Plasmodium falciparum	Malarial protease
2	BA, DB, FC, JA, KB... (C, F, J, D, G...)	ZINC ION	non-polymer		65.4	12	Chemie (ZN)
3	AD, CA, EB, GC, KA... (L, C, F, J, D...)	CARBONATE ION	non-polymer		60.0	12	Chemie (CO3) PubChem (19660)
4	AC, DA, EA, FA, HC... (I, C, J, D, G...)	SULFATE ION	non-polymer		96.1	16	Chemie (SO4)
5	AA, AB, BB, BC, BD... (B, E, I, L, F...)	PENTAETHYLENE GLYCOL	non-polymer		238.3	54	Chemie (1PE) PubChem (62551)
6	JB, VB, Y, Z (F, H, B)	NONAETHYLENE GLYCOL	non-polymer		414.5	4	Chemie (2PE) PubChem (4867)
7	GD, HD, ID, JD, KD... (A, B, C, D, E...)	water	water		18.0	3443	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 84 - 605 (UniProt: Q8IL11)

PDB	External Database	Details
Gln 152	Asn 152	engineered mutation
Gln 515	Asn 515	engineered mutation
Gln 546	Asn 546	engineered mutation
His 606	-	expression tag
His 607	-	expression tag
His 608	-	expression tag
His 609	-	expression tag
His 610	-	expression tag
His 611	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	704507.7
Non-Polymers*	Number of molecules	98
	Total formula weight	17567.0
All*	Total formula weight	722074.7

*Water molecules are not included.