3KOA
M296I mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA and GTP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3D polymerase | polymer | 476 | 53468.6 | 1 | UniProt (Q9QCE3) Pfam (PF00680) | Foot-and-mouth disease virus - type C | rna dependent rna polymerase |
| 2 | B (B) | RNA (5'-R(P*AP*UP*GP*GP*GP*C)-3') | polymer | 6 | 1931.2 | 1 | |||
| 3 | C (C) | RNA (5'-R(P*CP*CP*CP*G)-3') | polymer | 4 | 1215.8 | 1 | |||
| 4 | D, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | F (A) | DIPHOSPHATE | non-polymer | 173.9 | 1 | Chemie (DPO) | |||
| 6 | G, H (A, B) | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence modifications
A: 1 - 470 (UniProt: Q9QCE3)
| PDB | External Database | Details |
|---|---|---|
| Ile 296 | Met 2153 | engineered mutation |
| Ala 471 | - | expression tag |
| Ala 472 | - | expression tag |
| Leu 473 | - | expression tag |
| Glu 474 | - | expression tag |
| His 475 | - | expression tag |
| His 476 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 56615.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 222.6 | |
| All* | Total formula weight | 56838.2 |
