3KMW

Crystal structure of the ILK/alpha-parvin core complex (MgATP)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Integrin-linked kinase	polymer	271	30972.0	1	UniProt (Q13418) Pfam (PF07714) In PDB	Homo sapiens (human)	ILK
2	B	Alpha-parvin	polymer	129	14843.1	1	UniProt (Q9NVD7) Pfam (PF00307) In PDB	Homo sapiens (human)	Calponin-like integrin-linked kinase-binding protein, CH-ILKBP, Matrix-remodeling-associated protein 2, Actopaxin
3	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	A	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	1	Chemie (ATP)
5		water	water		18.0	309	Chemie (HOH)

Sequence modifications

A: 183 - 452 (UniProt: Q13418)

PDB	External Database	Details
Met -1	-	expression tag
Ser 346	Cys 346	engineered mutation
Ser 422	Cys 422	engineered mutation

B: 248 - 372 (UniProt: Q9NVD7)

PDB	External Database	Details
Gly -4	-	expression tag
Ser -3	-	expression tag
His -2	-	expression tag
Met -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45815.1
Non-Polymers*	Number of molecules	2
	Total formula weight	531.5
All*	Total formula weight	46346.6

*Water molecules are not included.