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3KMW

Crystal structure of the ILK/alpha-parvin core complex (MgATP)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Integrin-linked kinasepolymer27130972.01UniProt (Q13418)
Pfam (PF07714)
Homo sapiens (human)ILK
2B
(B)
Alpha-parvinpolymer12914843.11UniProt (Q9NVD7)
Pfam (PF00307)
Homo sapiens (human)Calponin-like integrin-linked kinase-binding protein, CH-ILKBP, Matrix-remodeling-associated protein 2, Actopaxin
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D
(A)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
5E, F
(A, B)
waterwater18.0309Chemie (HOH)
Sequence modifications
A: 183 - 452 (UniProt: Q13418)
PDBExternal DatabaseDetails
Met -1-expression tag
Ser 346Cys 346engineered mutation
Ser 422Cys 422engineered mutation
B: 248 - 372 (UniProt: Q9NVD7)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ser -3-expression tag
His -2-expression tag
Met -1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight45815.1
Non-Polymers*Number of molecules2
Total formula weight531.5
All*Total formula weight46346.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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