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3KJ2

Mcl-1 in complex with Bim BH3 mutant F4aE

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Induced myeloid leukemia cell differentiation protein Mcl-1polymer15817937.41UniProt (Q07820)
Pfam (PF00452)
Homo sapiens (human)Bcl-2-related protein EAT/mcl1, mcl1/EAT, Bcl-2-like protein 3, Bcl2-L-3
2B
(B)
Bcl-2-like protein 11polymer222782.11UniProt (O43521)
Pfam (PF08945)
Homo sapiens (human)Bcl2-L-11, Bcl2-interacting mediator of cell death
3C, D, E, G
(A, B)
ZINC IONnon-polymer65.44Chemie (ZN)
4F
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
5H, I
(A, B)
waterwater18.064Chemie (HOH)
Sequence modifications
A: 172 - 327 (UniProt: Q07820)
PDBExternal DatabaseDetails
Gly 170-expression tag
Ser 171-expression tag
B: 1 - 21 (UniProt: O43521)
PDBExternal DatabaseDetails
Glu 17Phe 159engineered mutation
Arg 22-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight20719.4
Non-Polymers*Number of molecules5
Total formula weight320.7
All*Total formula weight21040.1
*Water molecules are not included.

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PDB entries from 2024-10-30

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