3KFJ
Crystal Structure of the Grb2 SH2 Domain in Complex with a Flexible Ac-pY-E-N-NH2 Tripeptide Mimic
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Growth factor receptor-bound protein 2 | polymer | 117 | 13758.5 | 1 | UniProt (P62993) Pfam (PF00017) In PDB | Homo sapiens (human) | Adapter protein GRB2, SH2/SH3 adapter GRB2, Protein Ash |
2 | A | N-{(2S)-4-(methylamino)-4-oxo-2-[4-(phosphonooxy)benzyl]butanoyl}-L-alpha-glutamyl-L-aspartamide | non-polymer | 559.5 | 1 | BIRD (PRD_000635) Chemie (YEN) | |||
3 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
5 | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A: 53 - 163 (UniProt: P62993)
PDB | External Database | Details |
---|---|---|
His 164 | - | expression tag |
His 165 | - | expression tag |
His 166 | - | expression tag |
His 167 | - | expression tag |
His 168 | - | expression tag |
His 169 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 13758.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 654.7 | |
All* | Total formula weight | 14413.2 |