3KEK
Crystal Structure of Human MMP-13 complexed with a (pyridin-4-yl)-2H-tetrazole compound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Collagenase 3 | polymer | 167 | 18780.0 | 2 | UniProt (P45452) Pfam (PF00413) | Homo sapiens (human) | Matrix metalloproteinase-13, MMP-13 |
| 2 | C, D, I, J (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | E, F, G, K, L... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 4 | H, N (A, B) | trans-4-[(3-{2-[(4-fluorobenzyl)carbamoyl]-6-methylpyridin-4-yl}-1H-1,2,4-triazol-1-yl)methyl]cyclohexanecarboxylic acid | non-polymer | 451.5 | 2 | Chemie (3EK) | |||
| 5 | O, P (A, B) | water | water | 18.0 | 576 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37559.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1405.1 | |
| All* | Total formula weight | 38965.0 |
