3K72
Structure of integrin alphaX beta2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Integrin alpha-X | polymer | 1095 | 120708.2 | 2 | UniProt (P20702) Pfam (PF00092) Pfam (PF01839) Pfam (PF08441) Pfam (PF20805) Pfam (PF21520) | Homo sapiens (human) | Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150,95, Leu M5, CD11 antigen-like family member C |
| 2 | B, D (B, D) | Integrin beta-2 | polymer | 687 | 75943.0 | 2 | UniProt (P05107) Pfam (PF17205) Pfam (PF00362) Pfam (PF07965) | Homo sapiens (human) | Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta |
| 3 | E, I (E, I) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | F, J (F, J) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G21381MC) | |||
| 5 | G, H, K (G, H, K) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G62182OO) | |||
| 6 | AA, L, P, R, T... (D, A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
| 7 | M, N, O, Q, V... (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 8 | S (C) | alpha-D-mannopyranose | non-polymer | 180.2 | 1 | Chemie (MAN) |
Sequence modifications
A, C: 1 - 1084 (UniProt: P20702)
B, D: 1 - 683 (UniProt: P05107)
| PDB | External Database | Details |
|---|---|---|
| Gly 1085 | - | expression tag |
| Cys 1086 | - | expression tag |
| Gly 1087 | - | expression tag |
| Gly 1088 | - | expression tag |
| Leu 1089 | - | expression tag |
| Glu 1090 | - | expression tag |
| Asn 1091 | - | expression tag |
| Leu 1092 | - | expression tag |
| Tyr 1093 | - | expression tag |
| Phe 1094 | - | expression tag |
| Gln 1095 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp 678 | - | expression tag |
| Gly 679 | - | expression tag |
| Cys 680 | - | expression tag |
| Gly 681 | - | expression tag |
| Glu 682 | - | expression tag |
| Leu 684 | - | expression tag |
| Tyr 685 | - | expression tag |
| Phe 686 | - | expression tag |
| Gln 687 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 393302.4 | |
| Branched | Number of molecules | 7 |
| Total formula weight | 4430.1 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2049.2 | |
| All* | Total formula weight | 399781.7 |
