3K5T
Crystal structure of human diamine oxidase in space group C2221
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Diamine oxidase | polymer | 731 | 83463.8 | 1 | UniProt (P19801) Pfam (PF02727) Pfam (PF02728) Pfam (PF01179) In PDB | Homo sapiens (human) | Amiloride-sensitive amine oxidase [copper-containing], DAO, Amiloride-binding protein, ABP, Histaminase, Kidney amine oxidase, KAO |
| 2 | B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | A | COPPER (II) ION | non-polymer | 63.5 | 1 | Chemie (CU) | |||
| 4 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | water | water | 18.0 | 299 | Chemie (HOH) |
Sequence modifications
A: 21 - 751 (UniProt: P19801)
| PDB | External Database | Details |
|---|---|---|
| Arg 21 | Pro 21 | engineered mutation |
| Ser 592 | Thr 592 | variant |
| Asp 645 | His 645 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 83463.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 457.0 | |
| All* | Total formula weight | 84769.6 |
